U.S. regulatory momentum in psychedelics and peptides could open new commercial opportunities for PharmaTher’s PatchPrint™ automated manufacturing platform and PharmaPatch™ product platform as an attractive solution for compounding pharmacies, hospitals, research institutions, and commercial partners
Toronto, Ontario-April 20, 2026 – PharmaTher Holdings Ltd. (OTCQB: PHRRF) (CSE: PHRM) (“PharmaTher” or the “Company”), a specialty pharmaceutical company focused on microneedle patch technologies, believes it is well-positioned to benefit from two major U.S. regulatory developments: growing federal support for psychedelic medicine and advancing efforts to restore broader compounding access for select therapeutic peptides.
Two major U.S. federal shifts have created a compelling commercial opening for the Company’s microneedle patch solutions:
- Executive Order on Psychedelics: President Trump has signed the “Accelerating Medical Treatments for Serious Mental Illness” order. This mandates federal agencies to fast-track research, approvals, and patient access to psychedelic medicines.
- Peptide Reclassification: The FDA and HHS are moving to reclassify therapeutic peptides back to Category 1. This shift allows compounding pharmacies to once again produce these in-demand treatments, with a critical FDA advisory meeting set for July 23–24, 2026.
A Commercial Opportunity Taking Shape
PharmaTher believes growing U.S. regulatory momentum in psychedelics and therapeutic peptides could create a meaningful commercial opportunity for the Company. With PatchPrint™ as its automated microneedle patch manufacturing platform and PharmaPatch™ as its microneedle patch product platform, PharmaTher believes it has built an early position in two emerging high-value markets. The Company has previously reported positive PharmaPatch™ research results with psilocybin, LSD, DMT, and MDMA, completed an IND-enabling pharmacokinetic and tolerability study for its ketamine patch, and identified BPC-157, GHK-Cu, TB-500, and KPV as peptide candidates, supported by U.S. provisional patent application No. 64/034,315. PharmaTher believes that as psychedelic therapies advance and peptide compounding potentially expands, demand could grow for more precise, convenient, and patient-friendly delivery options such as microneedle patches.
“We believe the regulatory environment is beginning to open in both psychedelics and peptides, and we have already positioned the Company with PatchPrint™ and PharmaPatch™,” said Fabio Chianelli, Chief Executive Officer of PharmaTher. “As momentum builds in both markets, we see a meaningful opportunity to offer practical, patient-friendly, and differentiated microneedle patch solutions.”
The Commercial Opportunity for PatchPrint™
PatchPrint™ is PharmaTher’s proprietary automated tabletop microneedle patch 3D printer, covered by U.S. provisional patent application No. 64/015,408. The platform is being developed as a compact, end-to-end system that integrates dispensing, drying, demolding, and packaging into a single unit.
PharmaTher believes PatchPrint™ could be an attractive solution for 503A and 503B compounding pharmacies, hospitals, research institutions, and commercial partners seeking on-demand, small-footprint microneedle patch manufacturing.
The Company also sees PatchPrint™ as a potential driver of future revenue through system placements, formulation supply, consumables, service agreements, licensing, co-development, and contract manufacturing relationships.
Figure 1. Prototype rendering of PatchPrint™, PharmaTher’s automated tabletop microneedle patch production platform designed for end-to-end manufacturing.
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The Advantage of Microneedle Patches over Oral, Injectable, and Traditional Patch Delivery
PharmaTher believes microneedle patches offer important advantages over traditional delivery methods. Compared with oral delivery, they may avoid gastrointestinal degradation and first-pass metabolism. Compared with injections, they may improve convenience, reduce needle use, and support self-administration. Compared with traditional transdermal patches, microneedle patches may enable the delivery of a broader range of molecules, including peptides and other compounds that do not easily cross the skin barrier on their own.
The Company believes these advantages could make microneedle patches especially relevant in both peptides and psychedelics, where dosing control, patient experience, and ease of use are important.
Figure 2. Representative image of PharmaTher’s PharmaPatch™ ketamine microneedle patch and close-up of the microneedle array.
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A Platform Strategy Built for Growth
PharmaTher believes its strategy stands out because it combines three key elements in one integrated platform:
- PatchPrint™ as the manufacturing platform,
- PharmaPatch™ as the product platform, and
- Formulation IP to help protect and expand future commercial opportunities.
The Company believes it is positioned at an early stage of two potentially important market shifts: broader medical adoption of psychedelics and renewed compounding access for therapeutic peptides.
The Company notes that there can be no assurance as to the outcome, timing or scope of any regulatory change. However, PharmaTher believes the current policy direction is encouraging and supports continued execution of its peptide and psychedelic focused strategy.
About PatchPrint™
PatchPrint™ is PharmaTher’s proprietary automated tabletop microneedle patch manufacturing platform, covered by U.S. provisional patent application No. 64/015,408, and designed as a compact end-to-end system for on-demand patch production. PatchPrint™ could make microneedle patch manufacturing more practical for compounding pharmacies, hospitals, research institutions, and commercial partners by combining multiple production steps into one platform and supporting personalized, small-footprint manufacturing across peptides, psychedelics, biologics, and other high-value applications. The Company believes PatchPrint™ strengthens its long-term strategic position by supporting both proprietary PharmaPatch™ programs and other formulations developed for partners within a more integrated platform ecosystem.
About PharmaTher Holdings Ltd.
PharmaTher Holdings Ltd. (OTCQB: PHRRF) (CSE: PHRM) is a specialty pharmaceutical company focused on developing, acquiring, and commercializing pharmaceutical products and enabling technologies. The Company is advancing microneedle patch solutions through its PatchPrint™ automated manufacturing platform and PharmaPatch™ product platform, with opportunities across peptides, psychedelics, therapeutics and other high-value applications. For more information, visit PharmaTher.com.
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